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🇺🇸AP US History Unit 1 Review

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1.6 Cultural Interactions Between Europeans, Native Americans, and Africans

🇺🇸AP US History
Unit 1 Review

1.6 Cultural Interactions Between Europeans, Native Americans, and Africans

Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examWritten by the Fiveable Content Team • Last updated September 2025
🇺🇸AP US History
Unit & Topic Study Guides
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The Birth of a New Society

The clash of Native Americans, Europeans, and Africans produced a new society in both North and South America. Columbus’ voyage started a long chain of events that led to the decline of Native Americans, introduction of new plants and animals, and the forceful removal of millions of Africans. The story of the United States of America began as these three worlds converged. Here's the rewritten introduction for your study guide with improved readability:

Early English Settlement:

  • 1607: English settlers arrived in Jamestown, Virginia
  • Virginia Company: A joint-stock company that financed the settlement
  • Powhatan Nation: The indigenous confederacy the English encountered
Theodor de Bry, "Negotiating Peace With the Indians," 1634, Virginia Historical Society.

The Jamestown colony developed a complex relationship with Native Americans, marked by both cooperation and tension as each group pursued their interests.

Cooperation

  • Native Americans taught English how to grow corn
  • Trading partnerships for tools and furs
  • Initial diplomatic relations established
  • Some intermarriage occurred

Conflict

  • English desire to acquire more land created tensions
  • Cultural misunderstandings led to mistrust
  • Different concepts of land ownership led to disputes
  • Resource competition intensified over time

These early interactions at Jamestown set patterns that would repeat throughout European colonization of North America.

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Native American Trade with Europeans

Most Europeans looked down on Native Americans and saw them as inferior people who could be exploited for economic gain, converted to Christianity, and used as military allies. However, Native Americans were not passive victims of geopolitical forces beyond their control. As long as they remained healthy, they held their own in early exchanges. What they desired most was peaceful trade. 

In fact, French explorers recorded that Natives waved from shore, urging the Europeans to exchange metal items for beaver skins. The Natives did not perceive themselves as at a disadvantage in these proceedings. They thought it was crazy that the English would give them 20 knives for one beaver skin.  

Over time, cooperative encounters between Indians and Europeans became less frequent. English planters cleared the forests and fenced the fields, radically altering the ecological systems on which Indians depended. Natives discovered that the objects they desired from Europeans brought them into debt. To pay for these goods they hunted more aggressively and even further reduced the population of fur-bearing mammals. Natives grew dependent on trade for guns and ammunition and learned that wars would lead to a suspension of normal trade. 

Cultural Differences

One of the most significant differences between European and Native American worldviews was in the area of religion. European settlers generally practiced Christianity, a monotheistic religion, while Native Americans had a wide variety of religious beliefs and practices. These differences in religion often led to misunderstandings and conflicts between the two groups.

Comparing European and Native American Perspectives:

European ViewsNative American Views
Religion: Monotheistic ChristianityReligion: Diverse spiritual beliefs, often tied to nature
Gender Roles: Hierarchical with male dominanceGender Roles: More egalitarian with important roles for both sexes
Land Ownership: Private property as commodityLand Use: Communal approach with spiritual significance
Family Structure: Nuclear family focusedFamily Structure: Extended kinship networks

It is important to note that Native Americans were incredibly diverse, with hundreds of different languages and cultures that also varied based on region and climate. It is impossible to generalize anything to represent all Native Americans.

Cultural Adaptations and Exchanges:

  • Native to European: Introduction of corn, beans, and squash, which became important staples in European diets
  • European to Native: New technologies including iron tools, firearms, and horses that transformed native societies
  • Agricultural Practices: Europeans learned native farming techniques suitable for American environments
  • Medical Knowledge: Native Americans shared plant-based remedies with European settlers

Despite the conflicts and misunderstandings, these cultural exchanges played a crucial role in the development of colonial societies and influenced how both cultures evolved over time.

European Encroachment

As European colonization of the Americas increased, Native Americans faced significant challenges in defending and maintaining their political sovereignty, economic prosperity, religious beliefs, and concepts of gender relations. European encroachments on Native American lands and demands on their labor often threatened these aspects of Native American life, and Native Americans sought to protect them through a variety of means.

Native American Responses to European Expansion:

  • Diplomatic Strategies: Many Native groups negotiated treaties and agreements with European powers to protect their lands and rights
  • Alliance Formation: Some tribes formed strategic alliances with one European power against another or against rival Native groups
  • Military Resistance: Armed conflict to defend territories and resources became necessary as encroachment intensified
  • Cultural Preservation: Native communities worked to maintain traditions while selectively adopting beneficial European elements

In addition to diplomatic negotiations, Native Americans also resisted European encroachments through military action. While some Native American groups were able to achieve temporary victories, they were often ultimately unable to prevent the loss of their lands and the disruption of their communities.

Extended contact with Native Americans and Africans fostered a debate among European religious and political leaders about how non-Europeans should be treated. This debate was influenced by a variety of factors, including religious beliefs, cultural values, and evolving ideas about race.

European Justifications for Colonization:

  • Religious: Many Europeans claimed a duty to convert non-Europeans to Christianity
  • Cultural: Europeans often claimed they were "civilizing" peoples they considered primitive
  • Economic: The need for labor and resources was used to justify exploitation
  • Political: Europeans claimed the right to governance over territories they "discovered"

These justifications were often used to legitimize the exploitation of non-European labor and resources, as well as the conquest and colonization of non-European lands.

European Diseases

The spread of European diseases had a significant impact on Native American populations. Many Native American communities had not been exposed to the diseases that were common in Europe, and as a result, they had little or no immunity to these diseases. When Europeans arrived in the Americas, they brought with them diseases such as smallpox, measles, and influenza, which spread rapidly through Native American communities, often with devastating consequences.

In many cases, entire communities were wiped out by diseases to which they had no immunity. This led to significant population decline, as many Native Americans died from these diseases. The spread of European diseases also disrupted Native American societies and communities, as people were forced to flee or abandon their homes in order to escape the diseases.

Spanish Policy Towards Natives

One European who dissented from the views of most Europeans toward Native Americans was a Spanish priest named Bartolome de Las Casas. He had owned land and slaves in the West Indies and had fought in wars against the Indians, but eventually became an advocate for better treatment of the Indians. 

Las Casas became disillusioned with the treatment of Native Americans by European colonizers, and he began to speak out against the exploitation and mistreatment of Native Americans. He argued that Native Americans were entitled to the same rights and protections as Europeans, and he advocated for more humane treatment of Native Americans.

In the long term, he persuaded the Spanish king to institute the New Law of 1542. These laws ended indigenous slavery, halted forced native labor, and began to end the encomienda system, a Spanish labor system used in Spain's colonies which included forced labor of non-Christian indigenous peoples. 

However, despite these advances, the New Law was not always fully implemented, and Native Americans continued to face mistreatment and exploitation at the hands of European colonizers.

Vocabulary

The following words are mentioned explicitly in the College Board Course and Exam Description for this topic.

TermDefinition
cultural exchangeThe adoption and adaptation of useful aspects of culture between Europeans and Native Americans over time.
diplomatic negotiationsFormal discussions and agreements between European and Native American leaders to resolve conflicts and establish terms of interaction.
economic prosperityThe material well-being and wealth that Native Americans sought to maintain and defend.
gender rolesSocially defined expectations and behaviors associated with being male or female in a particular society.
land useDifferent approaches to utilizing and managing land, a key point of divergence between European and Native American perspectives.
military resistanceArmed opposition by Native Americans against European encroachment on their lands and demands for labor.
mutual misunderstandingsFailures in communication and comprehension between Europeans and Native Americans as each group attempted to interpret the other's actions and intentions.
political sovereigntyThe right of Native American peoples to govern themselves and maintain independent political authority.
racial justificationsArguments based on racial categories used by Europeans to justify the enslavement and subordination of Africans and Native Americans.
religionSystems of faith and worship that shaped European and Native American societies and their interactions.
subjugationThe process of bringing Africans and Native Americans under European control and domination.
worldviewsFundamental perspectives and beliefs about the world, including views on religion, gender roles, family structures, land use, and power.

Frequently Asked Questions

What were the main differences between how Europeans and Native Americans viewed land ownership?

Europeans and Native Americans had fundamentally different worldviews about land. Many Native societies saw land as a communal resource tied to kinship, spiritual practices, and seasonal use—you used, managed, and defended territory but didn’t “own” it as a commodity. Europeans saw land as private property: surveyed, titled, fenced, bought and sold, and the basis for wealth and political control. Those differences shaped early misunderstandings (trade vs. transfer, use rights vs. permanent sale) and fueled disputes as Europeans imposed legal claims, plantations, and settlement patterns. This contrast connects to CED ideas about divergent worldviews (land use, power) and explains Native resistance to encroachment (diplomacy and armed defense). For more on Topic 1.6, review the Fiveable study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM). Want practice questions that use these concepts on SAQs/DBQs? Try Fiveable’s practice bank (https://library.fiveable.me/practice/ap-us-history).

Why did Europeans and Native Americans have so many misunderstandings when they first met?

They misunderstood each other because they came with very different worldviews, languages, and social systems. Europeans viewed land as private property and sought permanent control; many Native societies saw land as communal and used through kinship and seasonal use—so Europeans’ land deals and fences didn’t make sense (CED KC-1.3.I.A). Religious differences, gender roles, and political authority also clashed: Europeans assumed hierarchical, centralized power while many Native polities used consensus or confederacies. Language barriers and different diplomatic/trade rituals produced misread signals (gift exchanges vs. permanent transfer). Disease made relationships uneven too: epidemics killed large numbers of Native people, changing power dynamics and fueling fear or blame. These misunderstandings shaped early trade, diplomacy, and later conflict, but over time both groups sometimes adopted useful practices from each other (cultural syncretism, KC-1.3.I.B). This kind of cause-and-effect reasoning shows up on AP short answers, DBQs, and LEQs—review Topic 1.6 for examples (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM). For extra practice, try Fiveable’s question bank (https://library.fiveable.me/practice/ap-us-history).

How did European attitudes toward Native Americans change over time?

At first many Europeans saw Native Americans as potential trading partners, allies, or souls to convert—so early contacts featured diplomacy, gift exchange, and missionary efforts (Spanish missions, Jesuit work). Over time attitudes shifted as contact deepened: misunderstandings about land use and gender, plus competition for resources, made Europeans view native land as something to claim and native labor as exploitable (encomienda system, fur trade). Religious and economic debates (e.g., Bartolomé de las Casas defending some natives) evolved into stricter racial and cultural justifications for dispossession and forced labor—ideas that fed later policies and resistance like the Pueblo Revolt or Powhatan conflicts. By 1607 Europeans increasingly framed Native peoples as obstacles to settlement or sources of labor rather than equal partners, which drove military resistance and loss of sovereignty. For review, see the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and practice Qs (https://library.fiveable.me/practice/ap-us-history) —both map directly to CED Learning Objective F.

What is cultural exchange and how did it happen between Europeans and Native Americans?

Cultural exchange is the give-and-take of goods, ideas, beliefs, and practices between groups. Between Europeans and Native Americans it happened through trade, everyday contact, missions, and conflict—producing the Columbian Exchange (foods, animals, and diseases), fur trade partnerships, and cultural syncretism (mixed religious practices and mestizaje). Europeans introduced horses, metal tools, guns, and Christianity; Native Americans introduced maize, potatoes, tobacco, and different land-use methods. Mutual misunderstandings about land, gender roles, and power (CED KC-1.3.I.A & I.B) shaped early interactions, but over time groups adopted useful elements of each other’s cultures. As European demands for land and labor grew, Native groups defended sovereignty through diplomacy and resistance (KC-1.3.I.C). For AP exam practice, you should be able to explain how and why perspectives changed (Learning Objective F) and use specific examples (Pueblo Revolt, fur trade, mestizaje). Review the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and try practice questions (https://library.fiveable.me/practice/ap-us-history).

I'm confused about how Native Americans tried to resist European colonization - can someone explain the different ways they fought back?

Native peoples resisted European colonization in several linked ways—diplomatic, military, cultural, economic, and by selective accommodation. Diplomatically they negotiated treaties, formed confederacies (like the Powhatan and Iroquois) and made strategic alliances. Militarily they resisted through wars and coordinated uprisings (examples to know: Metacom/King Philip’s War, the Pueblo Revolt) to defend sovereignty (CED KC-1.3.I.C; keywords: Powhatan Confederacy, Metacom, Pueblo Revolt, Iroquois Confederacy). Culturally they preserved or blended religious and social practices (cultural syncretism) to keep identity and resist conversion. Economically they controlled trade networks (fur trade) or disrupted colonial economies. Some groups also migrated or used legal/diplomatic pressure when possible. On the AP, be ready to explain how these forms of resistance show divergent worldviews and changing relationships (Learning Objective F). Review Topic 1.6 on Fiveable (study guide: https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and practice questions (https://library.fiveable.me/practice/ap-us-history).

What were the main disagreements between Europeans and Native Americans about gender roles and family structure?

They clashed because Europeans assumed a patriarchal, nuclear-family model while many Native societies organized gender, family, and power differently. Europeans expected male headship, male-controlled land and inheritance, and separate “private” household roles; they judged Native practices (matrilineal descent, women’s authority in Iroquois clans, communal land use, flexible marriage/divorce rules) as “improper.” Native peoples often tied kinship to extended networks and lineage (kinship networks, matrilineal clans), gave women important economic and political roles (food production, clan decisions), and linked gender to communal responsibilities rather than strict male supremacy. Europeans tried to impose their norms through missions, laws, and settlement patterns (Spanish missions, colonial gender expectations), producing sustained misunderstandings and resistance. For AP exam framing, put this under LO-F: divergent worldviews about gender/family shaped early diplomacy, conflict, and cultural syncretism (see the Topic 1.6 study guide: https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM). For more review/practice, check Unit 1 (https://library.fiveable.me/ap-us-history/unit-1) and the practice questions (https://library.fiveable.me/practice/ap-us-history).

How do I write a DBQ essay about European justifications for enslaving Africans?

Start with a clear thesis that answers “how and why Europeans justified enslaving Africans” (e.g., economically driven plus racial/religious rationales) and put it in your intro. Contextualize briefly: Atlantic economy, labor shortages in sugar/tobacco, and evolving racial ideas after 1492. Use at least four documents to support distinct claims: economic arguments (need for labor, profitability), legal/imperial texts (laws or royal charters), religious sources (calls to convert—civilizing language), and proto-scientific/racial texts (ideas of hierarchy). For two documents, analyze POV/purpose (who wrote it, why, audience) to show bias. Add one specific outside fact (e.g., the encomienda decline, Atlantic slave trade growth, or Middle Passage) as extra evidence. Tie documents to your line of reasoning and show complexity by acknowledging counterarguments (some Europeans criticized slavery—Las Casas’ shift) or changing justifications over time. For examples and practice DBQs, check the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and try practice questions (https://library.fiveable.me/practice/ap-us-history).

What's the difference between how Europeans treated Native Americans versus Africans?

Short answer: Europeans treated Native Americans and Africans differently in intent, legal status, and scale. Early European–Native contact often involved trade, diplomacy, and sometimes cultural exchange (fur trade, missions, mestizaje), with Native groups asserting sovereignty and resisting land/labor encroachment (Powhatan, Pueblo Revolt). Over time Europeans justified land seizure and forced labor with changing attitudes, but Native peoples remained political actors. Africans were increasingly incorporated into the Atlantic slave trade as chattel labor: kidnapped, transported via the Middle Passage, sold into lifetime, hereditary slavery, and racialized legal status (Atlantic slave trade, plantation labor). Africans formed kinship networks and Maroon communities, but they were treated as property rather than foreign sovereigns. On the AP exam this fits Topic 1.6 (CED keywords: encomienda, Middle Passage, cultural syncretism, mestizaje, Bartolomé de las Casas). For a deeper review see the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and practice questions (https://library.fiveable.me/practice/ap-us-history).

Why did some Europeans start debating whether it was okay to enslave Native Americans and Africans?

Some Europeans debated whether it was okay to enslave Native Americans and Africans for economic, legal, religious, and moral reasons. Economically, colonists wanted labor for plantations and the encomienda system forced Native labor, but abuses (and high Native death rates from disease) made some question its sustainability. Religiously and legally, missionaries and figures like Bartolomé de las Casas argued non-Christians still had rights and should be converted, not enslaved; others argued conquest gave Europeans authority. Those debates shifted as colonists turned increasingly to the Atlantic slave trade because Africans were thought to better survive plantation labor. Over time, cultural and racial justifications (Social Darwinist thinking later) hardened into systems that defended slavery. This fits AP Topic 1.6 (Learning Objective F): use these debates as evidence of changing European views and evolving justifications for subjugation. For the Topic 1.6 study guide see (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM). For more review and practice, check Unit 1 (https://library.fiveable.me/ap-us-history/unit-1) and AP practice problems (https://library.fiveable.me/practice/ap-us-history).

What does "political sovereignty" mean and how did Native Americans try to protect it?

"Political sovereignty" means a group's right to govern itself—make decisions about land use, laws, leadership, and foreign relations—without outside control. Native peoples tried to protect sovereignty in several ways: diplomacy (forming confederacies like the Iroquois or negotiating treaties with Europeans), selective adoption of European goods/strategies to strengthen their position, and organized resistance when diplomacy failed (e.g., Metacom’s War/King Philip’s War, the Pueblo Revolt). Some groups used economic strategies—controlling fur trade partnerships—to preserve autonomy; others used religious and cultural revival to reinforce internal unity (Pueblo resistance to missionization). These actions fit CED KC-1.3.I.C about defending political sovereignty through negotiations and military resistance. For more examples and AP-style practice, see the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and try practice problems (https://library.fiveable.me/practice/ap-us-history).

How did extended contact between Europeans, Native Americans, and Africans lead to new racial ideas?

Extended contact produced new racial ideas by turning cultural differences into hierarchical categories that justified unequal treatment. Early Spanish systems (encomienda) and the Atlantic slave trade made labor demands race-linked: Africans and many Native peoples were increasingly seen as appropriate sources of coerced labor. Mixed populations (mestizaje) led to caste systems that ranked people by ancestry, creating legal and social categories of “purity” vs. mixed heritage. Religious and political debates—e.g., Bartolomé de las Casas, the Valladolid controversy—forced Europeans to argue whether non-Europeans were full humans or souls to be converted, pushing toward racialized justifications for subjugation. Over time these ideas hardened into beliefs that skin color and descent determined status and rights, a key change you should connect to causes and continuity on AP short answers and LEQs. For a quick review, see the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM), the unit overview (https://library.fiveable.me/ap-us-history/unit-1), and practice questions (https://library.fiveable.me/practice/ap-us-history).

What are some specific examples of Europeans and Native Americans adopting parts of each other's culture?

Europeans and Native Americans borrowed lots from each other. Examples: European colonists adopted Native crops (maize, beans, squash) and hunting/fishing techniques—these changes were part of the Columbian Exchange and crucial for European survival. Native peoples adopted European goods and technologies like metal tools, firearms, and horses (which transformed Plains mobility and hunting). In the Spanish borderlands you get mestizaje and cultural syncretism: intermarriage, mixed Catholic–indigenous religious practices in missions, and new social castes. In the Northeast, the fur trade created kinship and diplomatic networks—Europeans learned Iroquois gift-giving and negotiation styles while Native economies shifted toward trade. The Pueblo Revolt and later Spanish accommodation show Native retention and selective adoption of Christianity and livestock. These kinds of exchanges are in the CED under divergent worldviews and cultural syncretism and often appear on short-answer/LEQ prompts. For a focused review, see the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and practice questions (https://library.fiveable.me/practice/ap-us-history).

What caused the shift from mutual misunderstanding to more hostile relationships between Europeans and Native Americans?

At first European–Native American contact involved trade and mutual curiosity, but it grew hostile as European demands and actions changed the balance. Key causes: expanding European settlement and land encroachment (conflicting concepts of land use), increased European demands for labor (encomienda systems, fur trade pressures), and disease-driven population collapse that disrupted Native societies and made competition over survivors and resources sharper. Cultural differences about religion, gender, and political authority hardened into justifications for domination (mestizaje, Spanish missions, racial ideas like those criticized by Bartolomé de las Casas). Native peoples responded with diplomacy and military resistance (Powhatan Confederacy, Pueblo Revolt, Metacom/King Philip). For AP exam work, connect these causes to KC-1.3.I.B–D and use specific examples on short answers or DBQs. Review Topic 1.6 on Fiveable’s study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and practice questions (https://library.fiveable.me/practice/ap-us-history).

How did religious beliefs play a role in European treatment of Native Americans and Africans?

Religion shaped how Europeans treated Native Americans and Africans in two big ways. First, missionaries and state churches pushed conversion—Spanish missions, English Puritan outreach, and Protestant/ Catholic competition justified expanding settlement and reshaping native life (see keywords: Spanish missions, mestizaje, cultural syncretism). Second, religious ideas were used as moral justifications for unequal treatment: some Europeans argued conversion and “civilizing” non-Europeans made subordination acceptable, while critics like Bartolomé de las Casas argued for better treatment. Those debates helped produce laws and practices (encomienda, Atlantic slave trade, Middle Passage) and influenced changing European policies and racial ideas over time (CED KC-1.3.I.D). On AP tasks you might be asked to explain changing perspectives or use primary sources to analyze these motivations—practice that skill in Topic 1.6 (study guide: https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM). For extra practice, try the AP question bank (https://library.fiveable.me/practice/ap-us-history).

What were the long-term consequences of these early cultural interactions for all three groups?

Early cultural contacts reshaped all three groups long-term. For Native Americans: massive population loss from Old World diseases, disruption of kinship and land use, resistance/diplomacy (Pueblo Revolt, Powhatan diplomacy), and cultural syncretism as tribes adopted European goods and sometimes Christianity—while losing political sovereignty as Europeans pushed for land and labor (CED KC-1.3.I.C). For Europeans: access to New World wealth, new colonial systems (encomienda), and debates over treatment of non-Europeans (Bartolomé de las Casas) that justified racial hierarchies and imperial expansion; economic growth drove more global engagement. For Africans: forcible displacement via the Atlantic slave trade and Middle Passage, creation of New World chattel slavery and caste systems, and Afro-Atlantic cultural retention (kinship networks, Maroon communities) that produced syncretic cultures and resistance. These developments show continuity and change you should connect on the exam (contextualization/causation). For a focused review, check the Topic 1.6 study guide (https://library.fiveable.me/ap-us-history/unit-1/cultural-interactions-between-europeans-native-americans-africans/study-guide/xKdK0605epqUHu2tUwYM) and hit practice questions (https://library.fiveable.me/practice/ap-us-history).