The years 1607 to 1754 saw great change in the Americas. The Native American population rapidly declined due to disease and conflicts with the newly arrived White Europeans. Europeans began to establish successful colonies, expanding first from Jamestown, then to places like the Puritan refuge in the Massachusetts Bay, the Catholic's colony in Maryland, the "holy experiment" in Pennsylvania, and the debtor's colony in Georgia. Life in the north, middle, Chesapeake, and southern colonies was drastically different.
As more and more people came to the Americas, trade heavily increased. A large part of that trade was the importation of enslaved Africans beginning in 1619. This trade would go on for another two centuries before finally being stopped.