Written by the Fiveable Content Team • Last updated August 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated August 2025
Definition
Non-competitive inhibitors are molecules that bind to an allosteric site on an enzyme, causing a conformational change in the enzyme's active site. This prevents the substrate from binding effectively, reducing enzymatic activity.
Enzyme kinetics: The study of how enzymes catalyze chemical reactions, including the effects of inhibitors on enzyme activity.
Feedback inhibition: A regulatory mechanism in which the end product of a metabolic pathway acts as a non-competitive inhibitor of an earlier enzyme in the pathway, slowing down its own production.
Enzyme-substrate complex: The temporary complex formed when an enzyme binds to its substrate(s) during a chemical reaction.