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Unit 4

4.4 Changes in Signal Transduction Pathways

1 min readโ€ขmay 30, 2020

Annika Tekumulla


Cellular Processes

Changes to any structure in the cell cycle can affect the signal transduction pathway. As we talked about earlier, the signal transduction pathway has the ability to alter cellular processes. Specifically, mutations can lead to detrimental effects on later responses.ย 

Mutations

Mutations have the ability to greatly impact the cell cycle. For example, mutations in the signal transduction pathway can prevent the cell from regulating its cell cycle. When the cell cycle is unregulated, it can result in unrestricted cell division that could lead to harmful conditions like cancer.ย 

We will go over more effects that mutations can have on cells in section 4.7 Regulation of Cell Cycle.

https://firebasestorage.googleapis.com/v0/b/fiveable-92889.appspot.com/o/images%2F-qB4UWLL7bS2Z.webp?alt=media&token=0b314e8e-97dc-49e2-b8ca-190e9ba1393f

Image courtesy of Giphy.

Chemicals

Along with mutations, chemicals have the ability to alter the signal transduction pathway. These chemicals can either activate or hamper the pathwayโ€™s response. For example, chemicals such as lead, polychlorinated biphenyls (PCBs), and ethanol have the ability to have neurotoxic effects with specific signal transduction pathways.

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