Secretin

Definition

Secretin is a hormone produced by the S-cells of the duodenum in response to acidic chyme entering from the stomach. It stimulates the pancreas to release bicarbonate-rich fluid, neutralizing stomach acid in the small intestine.

5 Must Know Facts For Your Next Test

1. Secretin is released when acidic chyme enters the duodenum.
2. Its primary function is to stimulate the pancreas to release bicarbonate.
3. Secretin also inhibits gastric emptying and gastric acid secretion.
4. It helps maintain an optimal pH for enzyme activity in the small intestine.
5. The discovery of secretin marked it as the first hormone ever identified.

Review Questions

Related terms

Gastrin:

A hormone that stimulates secretion of gastric acid by parietal cells in the stomach.

Cholecystokinin (CCK): A hormone that stimulates digestion of fats and proteins by promoting bile and pancreatic enzyme release.

Pancreatic Enzymes: Digestive enzymes produced by the pancreas that aid in breaking down carbohydrates, proteins, and fats.