The lethal dose 50% (LD50) is the dose at which 50% of the population or test subjects die from exposure to a substance.
Therapeutic Index: The therapeutic index is a measure of the safety and effectiveness of a drug, calculated by dividing the LD50 by the ED50.
Margin of Safety: The margin of safety refers to the difference between the therapeutic dose and toxic dose, indicating how much room for error exists when administering a medication.