🦠microbiology review

Gluten

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Gluten is a group of proteins found in wheat and related grains, including barley and rye. It is known for causing adverse health reactions in individuals with certain autoimmune disorders.

5 Must Know Facts For Your Next Test

  1. Gluten can trigger an autoimmune response in individuals with celiac disease, leading to damage in the small intestine.
  2. Non-celiac gluten sensitivity (NCGS) can cause symptoms similar to celiac disease but does not involve an autoimmune response.
  3. The primary proteins in gluten are gliadin and glutenin, which contribute to its elastic properties.
  4. Ingestion of gluten by individuals with celiac disease leads to the production of specific antibodies that attack the intestinal lining.
  5. Dermatitis herpetiformis is a skin manifestation of celiac disease caused by gluten ingestion.

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