The Th1 response is a type of adaptive immune response that is primarily focused on the elimination of intracellular pathogens, such as viruses and certain bacteria. It is characterized by the activation of T helper 1 (Th1) cells, which produce specific cytokines that coordinate the body's defense against these types of infections.
T Helper Cells: T helper cells, also known as CD4+ T cells, are a subtype of T cells that play a crucial role in coordinating the adaptive immune response. They provide help and support to other immune cells, such as B cells and cytotoxic T cells, to effectively eliminate pathogens.
Cytokines: Cytokines are signaling molecules produced by various cells, including immune cells, that play a vital role in cell-to-cell communication and the regulation of immune responses. They can have pro-inflammatory or anti-inflammatory effects, depending on the specific cytokine and the context of the immune response.
Cell-Mediated Immunity: Cell-mediated immunity refers to the immune response that is primarily driven by the activation and function of T cells, as opposed to the antibody-mediated immune response driven by B cells. It is particularly effective against intracellular pathogens and plays a key role in the Th1 response.