🦠microbiology review

Formalin

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Formalin is a solution of formaldehyde in water, commonly used as a disinfectant and preservative. It is effective in killing microorganisms and preserving biological specimens.

5 Must Know Facts For Your Next Test

  1. Formalin is typically composed of 37% formaldehyde by weight in water.
  2. It is widely used for sterilizing surgical instruments and decontaminating surfaces.
  3. Formalin works by denaturing proteins and nucleic acids, leading to cell death.
  4. Prolonged exposure to formalin can be toxic, causing irritation to the skin, eyes, and respiratory system.
  5. Its effectiveness can be influenced by factors such as concentration, temperature, and contact time.

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