Insertion

Definition

Insertion is a type of mutation where one or more nucleotide base pairs are added into a DNA sequence. This can lead to changes in the protein encoded by the gene.

5 Must Know Facts For Your Next Test

1. Insertion mutations can disrupt the reading frame of a gene, leading to frameshift mutations.
2. Insertion mutations can occur naturally or be induced by mutagens.
3. The effects of an insertion can vary from benign to severe, depending on its location and size.
4. Some insertions can lead to the creation of new genetic material, potentially causing evolutionary changes.
5. Molecular techniques like PCR and sequencing are used to detect insertion mutations.

Review Questions

• What effect does an insertion mutation have on the reading frame of a gene?
• How can insertion mutations be detected in a laboratory setting?
• What factors determine whether an insertion mutation will have a significant impact on an organism?

Related terms

Deletion: A type of mutation where one or more nucleotide base pairs are removed from a DNA sequence.

Frameshift Mutation:

A genetic mutation caused by insertions or deletions that change the reading frame of a codon sequence.

Mutagen:

An agent that causes genetic mutation, which can include chemicals, radiation, and viruses.