The Columbian Exchange was the transfer of plants, animals, diseases, and people between the Old World and the New World after 1492. For Europeans, it created economic opportunities through new crops like potatoes and new plantation commodities like sugar and tobacco. For indigenous peoples, it was catastrophic: diseases like smallpox and measles, to which they had no immunity, collapsed populations across the Americas. This demographic catastrophe, combined with the labor demands of plantation agriculture, drove the expansion of the transatlantic slave trade. Europeans forcibly transported enslaved Africans across the Middle Passage to work on plantations in the Caribbean and the Americas. The exchange also shifted Europe's economic center of gravity from the Mediterranean to Atlantic port cities like Antwerp, Amsterdam, Bristol, and London.
Explain the connection between the Columbian Exchange, the collapse of indigenous populations, and the expansion of the slave trade. Use at least two specific pieces of evidence.