Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Phosphorylation is a biochemical process where a phosphate group is added to an organic molecule. It's crucial in many cellular processes, including metabolism, transcription, and cell signaling.
An enzyme that catalyzes the transfer of phosphate groups from high-energy donor molecules (like ATP) to specific target molecules in a process called phosphorylation.
Dephosphorylation: The removal of a phosphate group from an organic compound by hydrolysis. It's essentially the reverse process of phosphorylation and can also regulate protein function.
As mentioned earlier, this is how cells communicate and respond to their environment. Phosphorylation plays a key role in transmitting these signals within cells.