๐Ÿงฌap biology review

Nucleotide substitution

Written by the Fiveable Content Team โ€ข Last updated August 2025
Verified for the 2027 exam
Verified for the 2027 examโ€ขWritten by the Fiveable Content Team โ€ข Last updated August 2025

Definition

A type of point mutation in which one nucleotide is replaced by a different nucleotide in the DNA sequence, without breaking the DNA backbone or creating fragments.

AP course connection

Topic 6.7: 6.7 Mutations

Unit 6

"Nucleotide substitution" also found in: