AP Biology MCQs
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AP Biology practice questions by unit
Fiveable has 26,558 AP Biology multiple-choice practice questions across 8 units, plus 455 stimulus-based question sets built around a source. Practice one unit or topic at a time.
- Unit 1 โ Chemistry of Life: 1,629 multiple-choice questions, 56 stimulus sets
- Unit 2 โ Cell Structure and Function: 4,474 multiple-choice questions, 81 stimulus sets
- Unit 3 โ Cellular Energetics: 2,352 multiple-choice questions, 37 stimulus sets
- Unit 4 โ Cell Communication and Cell Cycle: 2,763 multiple-choice questions, 42 stimulus sets
- Unit 5 โ Heredity: 2,183 multiple-choice questions, 38 stimulus sets
- Unit 6 โ Gene Expression and Regulation: 3,416 multiple-choice questions, 61 stimulus sets
- Unit 7 โ Natural Selection: 5,618 multiple-choice questions, 89 stimulus sets
- Unit 8 โ Ecology: 4,123 multiple-choice questions, 51 stimulus sets
Sample AP Biology practice question
A mutation prevents a cell from producing functional cyclin-dependent kinase (CDK), but cyclin proteins are still made. What effect on the cell cycle is most likely?
Cells fail to pass key checkpoints because cyclin-CDK complexes cannot phosphorylate targets
Cells speed through key checkpoints because cyclins alone can activate DNA replication proteins
Cells bypass key checkpoints because loss of CDK eliminates all checkpoint signaling proteins entirely
Cells complete normal mitosis because CDK is required only for cytokinesis, not checkpoints
Explanation
Linking checkpoint control to cyclin-CDK activity explains the disruption. Without functional CDK, cyclins cannot activate the kinase activity needed to phosphorylate proteins that drive progression through G1/S and G2/M checkpoints.
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- AP Biology unit tests: a timed practice test for every unit
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