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Chargaff’s Rule

Written by the Fiveable Content Team • Last updated August 2025
Verified for the 2027 exam
Verified for the 2027 examWritten by the Fiveable Content Team • Last updated August 2025

Definition

Chargaff's Rule states that in DNA, the amount of adenine (A) equals the amount of thymine (T), and the amount of guanine (G) equals the amount of cytosine (C).

AP course connection

Topic 1.6: 1.6 Nucleic Acids

Unit 1

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