🦠microbiology review

Spontaneous mutation

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

A spontaneous mutation is a change in the genetic sequence that occurs without external influence, typically during DNA replication. These mutations can lead to variations within microbial populations.

AP course connection

Topic 11.5: 11.5 Mutations

Unit 11

5 Must Know Facts For Your Next Test

  1. Spontaneous mutations occur at a relatively low but constant rate.
  2. They can result from errors in DNA replication, spontaneous lesions, or transposable elements.
  3. Spontaneous mutations can be beneficial, neutral, or harmful to the organism.
  4. These mutations contribute to genetic diversity within microbial communities.
  5. Natural selection acts on these mutations, influencing microbial evolution.

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