Enteroinvasive E. coli (EIEC)

Definition

Enteroinvasive E. coli (EIEC) is a pathogenic strain of Escherichia coli that invades and multiplies within intestinal epithelial cells, causing inflammation and dysentery-like symptoms. It closely resembles Shigella in its pathogenic mechanisms.

5 Must Know Facts For Your Next Test

1. EIEC causes disease by invading and destroying the epithelial lining of the colon.
2. Symptoms of EIEC infection include fever, abdominal cramps, and severe diarrhea with blood and mucus.
3. Transmission typically occurs through the ingestion of contaminated food or water.
4. The pathogenesis of EIEC involves a type III secretion system to inject virulence factors into host cells.
5. Diagnosis often involves stool cultures and molecular techniques to identify specific genetic markers.

Review Questions

• What are the primary symptoms associated with an EIEC infection?
• How does EIEC invade host cells?
• What methods are used to diagnose an infection caused by Enteroinvasive E. coli?

Related terms

Shigella: A genus of bacteria closely related to EIEC that also causes dysentery by invading intestinal epithelial cells.

Escherichia coli: A diverse group of bacteria commonly found in the intestines of humans and animals; some strains are pathogenic.

Type III Secretion System: A needle-like protein appendage used by some bacteria, including EIEC, to inject virulence factors into host cells.