Quiescent

Definition

Quiescent refers to a state in which cells are not actively dividing but are metabolically active. These cells are in a resting phase, often referred to as the G0 phase of the cell cycle.

5 Must Know Facts For Your Next Test

1. Quiescent cells can re-enter the cell cycle in response to specific signals.
2. The G0 phase is distinct from the G1 phase, where cells prepare for DNA synthesis.
3. Many differentiated cells, such as neurons and muscle cells, are typically quiescent.
4. Quiescence is crucial for tissue homeostasis and preventing uncontrolled cell proliferation.
5. Cellular quiescence involves regulatory mechanisms that maintain cell viability without progression through the cell cycle.

Review Questions

• What phase of the cell cycle do quiescent cells reside in?
• Can quiescent cells re-enter the cell cycle? If so, under what conditions?
• Why is cellular quiescence important for tissue homeostasis?

Related terms

Cell Cycle: A series of phases that a cell goes through from one division to the next.

G1 Phase: The first gap phase where the cell grows and prepares for DNA synthesis.

Differentiation: The process by which a less specialized cell becomes a more specialized cell type.