Sclerotome

Definition

A sclerotome is a group of mesodermal cells in a vertebrate embryo that differentiates into bones, cartilage, and connective tissues of the axial skeleton. It originates from the segmental division of the somites during embryonic development.

Related terms

Somite:

A segmented block of mesoderm found in pairs along the head-to-tail axis of a developing embryo that differentiates into various tissues including muscle, vertebrae, and dermis.

Mesoderm:

The middle layer of an embryo in early development that gives rise to muscles, bones, and circulatory systems among other structures.

Axial Skeleton:

The part of the skeleton that includes the skull, vertebral column, ribs, and sternum, serving as a central framework for supporting and protecting an organism's vital organs