Toxicogenomics

Definition

Toxicogenomics is the study of how genomes respond to environmental toxins. It combines toxicology with genomics to understand the genetic basis of adverse effects caused by toxic substances.

5 Must Know Facts For Your Next Test

1. Toxicogenomics involves analyzing gene expression changes in response to toxicants.
2. It utilizes high-throughput technologies like microarrays and RNA sequencing.
3. The field aims to identify biomarkers for early detection of toxicity.
4. Toxicogenomics helps in understanding individual susceptibility to toxins based on genetic makeup.
5. It's pivotal in drug development for assessing potential toxicity of new pharmaceutical compounds.

Related terms

Genomics:

The study of an organism's complete set of DNA, including all its genes.

Transcriptomics:

The study of the RNA molecules produced by a genome.

Pharmacogenomics:

The study of how genes affect a person's response to drugs.