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Exergonic reaction

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

An exergonic reaction is a chemical reaction that releases energy by breaking down complex molecules into simpler ones. It often involves the release of heat and increases the entropy of the system.

5 Must Know Facts For Your Next Test

  1. Exergonic reactions have a negative Gibbs free energy (ΔG < 0).
  2. These reactions are spontaneous and do not require an input of energy.
  3. Cellular respiration is a prime example of an exergonic reaction in microbial metabolism.
  4. Enzymes can catalyze exergonic reactions to increase their reaction rates.
  5. The energy released from exergonic reactions can be harnessed for cellular processes like ATP synthesis.

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