Cell junctions

Definition

Cell junctions are specialized structures that connect cells to each other or to the extracellular matrix. They play critical roles in maintaining tissue integrity and facilitating communication between cells.

5 Must Know Facts For Your Next Test

1. Cell junctions are crucial for maintaining the physical barrier of epithelial tissues, which is part of innate nonspecific host defenses.
2. There are three main types of cell junctions: tight junctions, adherens junctions, and gap junctions.
3. Tight junctions prevent the passage of molecules and ions through the space between cells.
4. Adherens junctions connect the actin cytoskeleton of one cell with that of another, providing mechanical stability.
5. Gap junctions allow direct communication between cells by permitting the passage of small molecules and ions.

Related terms

Epithelial Tissue: A type of tissue that forms a protective barrier on body surfaces and lines internal cavities.

Extracellular Matrix: A complex network of proteins and carbohydrates surrounding cells, providing structural support.

Innate Immunity:

The body's first line of defense against pathogens, involving physical barriers, chemical signals, and immune cells.