🦠microbiology review

Bacterial cell walls

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Bacterial cell walls are rigid structures that surround the cell membrane, providing shape and protection. They are primarily composed of peptidoglycan, a unique polymer found only in bacteria.

5 Must Know Facts For Your Next Test

  1. Bacterial cell walls are categorized into Gram-positive and Gram-negative based on their structure and staining properties.
  2. Gram-positive bacterial cell walls have a thick peptidoglycan layer, whereas Gram-negative bacterial cell walls have a thin peptidoglycan layer and an outer membrane.
  3. The peptidoglycan layer is essential for maintaining the structural integrity of the bacterial cell.
  4. Lysozyme, an enzyme found in human tears and saliva, can break down the peptidoglycan layer of bacterial cell walls.
  5. Certain antibiotics, like penicillin, target the synthesis of peptidoglycan, making them effective against bacterial infections.
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