Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Telbivudine is an antiviral medication used to treat chronic hepatitis B virus (HBV) infections. It works by inhibiting viral DNA synthesis.
5 Must Know Facts For Your Next Test
Telbivudine is classified as a nucleoside analogue reverse transcriptase inhibitor (NRTI).
It specifically targets the hepatitis B virus, reducing viral load in infected individuals.
Resistance to telbivudine can develop, often due to mutations in the HBV polymerase gene.
Common side effects include fatigue, headache, and elevated levels of creatine kinase.
It is important to monitor liver function and kidney function during treatment with telbivudine.
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Related terms
Hepatitis B Virus (HBV): A DNA virus that causes liver infection leading to both acute and chronic disease.
Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs): A class of antiviral drugs that inhibit viral replication by incorporating into viral DNA.