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Proton motive force

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Proton motive force (PMF) is the potential energy stored across a membrane due to the difference in proton concentration and electrical charge. It is essential for ATP synthesis during cellular respiration.

5 Must Know Facts For Your Next Test

  1. PMF is generated by the electron transport chain during cellular respiration.
  2. It drives ATP synthesis by ATP synthase through chemiosmosis.
  3. PMF consists of two components: a chemical gradient (ΔpH) and an electrical gradient (Δψ).
  4. Disruption of PMF can halt ATP production, affecting cell survival.
  5. In bacteria, PMF is also used for transporting nutrients and powering flagella.

Review Questions

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Proton motive force Definition - Microbiology Key Term | Fiveable