Penciclovir

Definition

Penciclovir is an antiviral medication used to treat herpes simplex virus infections, particularly cold sores. It works by inhibiting viral DNA replication, thus controlling the spread of the virus.

5 Must Know Facts For Your Next Test

1. Penciclovir is commonly applied topically in cream form for treating cold sores.
2. It specifically targets the herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).
3. Penciclovir has a longer intracellular half-life compared to acyclovir, making it effective for sustained antiviral activity.
4. The medication is most effective when applied at the first sign of a cold sore outbreak.
5. Common side effects include mild pain, irritation, or redness at the application site.

Review Questions

• What type of infections is penciclovir primarily used to treat?
• How does penciclovir inhibit the spread of herpes simplex viruses?
• What are common side effects associated with topical penciclovir use?

Related terms

Acyclovir: An antiviral drug related to penciclovir, also used to treat herpes simplex virus infections.

Herpes Simplex Virus (HSV): A group of viruses that cause infections in humans, including cold sores and genital herpes.

Topical Cream: A medication applied directly to the skin to treat local infections or conditions.