🦠microbiology review

Nonenveloped virus

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

A nonenveloped virus is a type of virus that lacks a lipid bilayer surrounding its capsid. These viruses are typically more resistant to environmental factors and disinfectants.

5 Must Know Facts For Your Next Test

  1. A nonenveloped virus has only a protein coat called a capsid, without an outer lipid envelope.
  2. Nonenveloped viruses are generally more stable in harsh conditions, such as acidic environments or high temperatures.
  3. They often enter host cells through endocytosis rather than membrane fusion.
  4. Examples include adenoviruses, parvoviruses, and noroviruses.
  5. The absence of an envelope makes them less susceptible to alcohol-based disinfectants.

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