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Cholecystokinin

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Cholecystokinin (CCK) is a hormone produced in the small intestine that stimulates the digestion of fats and proteins. It also triggers the release of digestive enzymes from the pancreas and bile from the gallbladder.

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5 Must Know Facts For Your Next Test

  1. CCK is released by cells in the duodenum in response to the presence of chyme.
  2. It enhances digestion by slowing gastric emptying and promoting satiety.
  3. CCK stimulates the gallbladder to contract and release stored bile into the intestine.
  4. It prompts the pancreas to secrete its digestive enzymes, such as trypsin and lipase.
  5. CCK also acts on the brain to produce a feeling of fullness after eating.

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