Gastrin

Definition

Gastrin is a hormone produced by the stomach's G-cells that stimulates the secretion of gastric acid. It plays a crucial role in the digestive process by promoting the breakdown of proteins and absorption of nutrients.

5 Must Know Facts For Your Next Test

1. Gastrin is secreted primarily in response to food intake, particularly proteins.
2. It acts on parietal cells in the stomach lining to increase gastric acid production.
3. Gastrin also promotes gastric motility and growth of the gastric mucosa.
4. High levels of gastrin can be associated with certain medical conditions, such as Zollinger-Ellison syndrome.
5. The secretion of gastrin is regulated through a feedback mechanism involving somatostatin.

Review Questions

Related terms

Parietal_Cells: Cells in the stomach lining responsible for secreting hydrochloric acid.

Somatostatin: A hormone that inhibits the release of several other hormones, including gastrin.

Zollinger-Ellison_Syndrome: A condition characterized by excessive secretion of gastrin leading to peptic ulcers.