X-linked

Definition

X-linked refers to genes located on the X chromosome. These genes can exhibit unique patterns of inheritance, particularly affecting males more frequently due to their single X chromosome.

5 Must Know Facts For Your Next Test

1. X-linked traits are more commonly expressed in males because they have only one X chromosome.
2. Females have two X chromosomes, which allows for a second copy of the gene that can mask the effects of a recessive allele.
3. Hemophilia and color blindness are classic examples of X-linked recessive disorders.
4. Males inherit their X chromosome from their mother and Y chromosome from their father.
5. A female carrier of an X-linked recessive disorder has a 50% chance of passing the gene to her sons, who will express the trait.

Related terms

Autosomal: Pertains to chromosomes that are not sex chromosomes (X or Y).

Y-linked: Refers to genes located on the Y chromosome, typically passed from father to son.

Carrier: An individual who has one copy of a recessive allele that causes disease in individuals that are homozygous for this allele.