🧬Systems Biology

Unit 1 – Systems Biology: Core Concepts & Principles

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Unit 2 – Molecular Biology: Genes to Metabolites

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Unit 3 – Omics Technologies in Systems Biology

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Unit 4 – Biological Databases & Bioinformatics Tools

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Unit 5 – Network Biology: Graph Theory & Analysis

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Unit 6 – Dynamic Systems Theory and Feedback Loops

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Unit 7 – Modeling Biological Systems Mathematically

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Unit 8 – Computational Modeling in Systems Biology

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Unit 9 – Biological Networks: Robustness & Modularity

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Unit 10 – Gene Regulatory Networks and Epigenetics

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Unit 11 – Metabolic Networks & Flux Balance Analysis

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Unit 12 – Signaling Networks & Systems Pharmacology

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Unit 13 – Multi-Scale Modeling: Molecules to Tissues

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Unit 14 – Synthetic Biology: Circuit Design Basics

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Unit 15 – Disease Modeling & Network Drug Discovery

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Unit 16 – Systems Biology: Case Studies & Applications

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What do you learn in Systems Biology

Systems Biology explores how complex biological systems function as a whole. You'll study the interactions between genes, proteins, and biochemical networks. The course covers computational modeling, network analysis, and high-throughput data integration. You'll learn to apply mathematical and computational tools to understand biological processes at multiple scales, from cells to ecosystems.

Is Systems Biology hard?

Systems Biology can be challenging because it combines biology, math, and computer science. The interdisciplinary nature can be tough if you're not comfortable with all three areas. That said, many students find it rewarding once they get the hang of it. The key is to stay on top of the material and not let the math or coding parts intimidate you.

Tips for taking Systems Biology in college

  1. Use Fiveable Study Guides to help you cram 🌶️
  2. Practice coding regularly - don't leave it all for the last minute
  3. Form study groups to tackle complex problems together
  4. Review calculus and statistics concepts before the course starts
  5. Get comfortable with data visualization tools early on
  6. Watch "A Beautiful Mind" for inspiration on mathematical modeling
  7. Read "The Selfish Gene" by Richard Dawkins for insights on evolutionary systems
  8. Attend office hours to clarify tough concepts

Common pre-requisites for Systems Biology

  1. Molecular Biology: Dives into the structure and function of DNA, RNA, and proteins. You'll learn about gene expression and regulation at the molecular level.

  2. Calculus: Covers differential and integral calculus, which are essential for understanding mathematical models in systems biology. You'll learn to analyze rates of change and accumulation in biological systems.

  3. Introduction to Programming: Teaches basic programming concepts and languages like Python or R. You'll develop skills to manipulate and analyze large biological datasets.

Classes similar to Systems Biology

  1. Computational Biology: Focuses on using computational methods to analyze biological data. You'll learn about sequence alignment, genome assembly, and protein structure prediction.

  2. Bioinformatics: Combines biology, computer science, and statistics to analyze biological data. You'll work with large datasets from genomics, proteomics, and other high-throughput experiments.

  3. Network Biology: Explores biological systems as networks of interacting components. You'll study graph theory and its applications to cellular and molecular networks.

  4. Synthetic Biology: Applies engineering principles to design and construct new biological parts, devices, and systems. You'll learn about genetic circuits, metabolic engineering, and biosensors.

  1. Bioinformatics: Combines biology, computer science, and statistics to analyze biological data. Students learn to develop algorithms and tools for processing large-scale biological datasets.

  2. Computational Biology: Focuses on using mathematical and computational approaches to solve biological problems. Students study modeling, simulation, and data analysis techniques for understanding complex biological systems.

  3. Bioengineering: Applies engineering principles to biological and medical systems. Students learn to design and develop new technologies for healthcare, biotechnology, and environmental applications.

  4. Quantitative Biology: Emphasizes the use of mathematical and statistical methods in biological research. Students develop skills in data analysis, modeling, and experimental design for studying biological phenomena.

What can you do with a degree in Systems Biology?

  1. Bioinformatics Scientist: Develops algorithms and software tools to analyze biological data. They work on projects like genome sequencing, protein structure prediction, and drug discovery.

  2. Computational Biologist: Uses mathematical and computational methods to study biological systems. They create models to simulate and predict the behavior of complex biological processes.

  3. Data Scientist in Biotechnology: Analyzes large-scale biological data to extract meaningful insights. They work on projects like personalized medicine, drug development, and agricultural biotechnology.

  4. Systems Biology Researcher: Investigates how biological systems function as a whole. They design experiments and develop models to understand the interactions between different components of biological systems.

Systems Biology FAQs

  1. How much programming do I need to know? You should be comfortable with basic programming concepts and at least one language like Python or R. The course will likely include coding assignments and data analysis projects.

  2. Can I specialize in a specific area of Systems Biology? Yes, you can often focus on areas like metabolic networks, gene regulatory networks, or ecological systems, depending on your interests and the course offerings.

  3. Is Systems Biology useful for medical research? Absolutely! Systems Biology approaches are increasingly important in understanding diseases and developing personalized treatments. Many pharmaceutical companies employ systems biologists for drug discovery and development.



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© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.