Gauche conformation

Definition

Gauche conformation is a specific spatial arrangement of atoms in organic molecules where two substituents on adjacent carbon atoms are closer than the most energetically favorable position, typically within a 60-degree dihedral angle. This conformation is less stable than the staggered conformation due to increased steric hindrance.

Related terms

Staggered Conformation:

A more energetically favorable molecular arrangement in which substituents on adjacent carbons are as far apart as possible, minimizing steric hindrance.

Steric Hindrance:

The repulsion between two groups within a molecule due to their size, shape, or position that prevents them from coming too close to each other.

Dihedral Angle:

The angle between two planes defined by four different atoms, commonly used to describe the orientation of substituents in organic molecules