Vancomycin-resistant enterococci (VRE)

Definition

Vancomycin-resistant enterococci (VRE) are strains of the Enterococcus bacteria that have developed resistance to vancomycin, an antibiotic used to treat serious infections. VRE infections are particularly concerning in healthcare settings due to limited treatment options.

5 Must Know Facts For Your Next Test

1. VRE is primarily transmitted via direct contact with contaminated surfaces or person-to-person contact.
2. The genes responsible for vancomycin resistance in enterococci are often located on plasmids, which can be transferred between bacteria.
3. Infections caused by VRE can include urinary tract infections, bacteremia, and endocarditis.
4. Risk factors for VRE infection include prolonged hospital stays, immunocompromised status, and previous antibiotic use.
5. Treatment options for VRE infections are limited and may include linezolid or daptomycin.

Related terms

Antibiotic Resistance:

The ability of bacteria to survive and grow in the presence of antibiotics that would normally kill them or inhibit their growth.

Nosocomial Infection: An infection acquired in a hospital or healthcare setting.

Plasmid:

A small DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently.