Phage conversion

Definition

Phage conversion is a process where a bacterium acquires new traits due to the integration of prophage DNA into its genome. This can result in changes such as increased virulence or antibiotic resistance.

5 Must Know Facts For Your Next Test

1. Phage conversion often occurs when a bacteriophage integrates its genetic material into the bacterial chromosome.
2. This process can lead to the expression of new genes that were not originally present in the bacterium.
3. A classic example is the diphtheria toxin, which is produced by Corynebacterium diphtheriae only when infected by a specific phage.
4. Phage conversion can contribute to the spread of antibiotic resistance among bacterial populations.
5. It plays a significant role in the evolution and adaptation of bacterial pathogens.

Related terms

Bacteriophage:

A virus that infects and replicates within bacteria.

Prophage:

The viral DNA that is integrated into the bacterial genome during lysogeny.

Lysogenic Cycle:

A viral replication cycle where the virus integrates its DNA into the host genome without immediately destroying the host cell.