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Toxicogenomics

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Toxicogenomics is the study of how genomes respond to environmental toxins. It combines toxicology with genomics to understand the genetic basis of adverse effects caused by toxic substances.

5 Must Know Facts For Your Next Test

  1. Toxicogenomics involves analyzing gene expression changes in response to toxicants.
  2. It utilizes high-throughput technologies like microarrays and RNA sequencing.
  3. The field aims to identify biomarkers for early detection of toxicity.
  4. Toxicogenomics helps in understanding individual susceptibility to toxins based on genetic makeup.
  5. It's pivotal in drug development for assessing potential toxicity of new pharmaceutical compounds.

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