Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
A systemic infection is an infection that has spread throughout the body, affecting multiple organs and tissues. It often results from pathogens entering the bloodstream and disseminating from the initial site of infection.
5 Must Know Facts For Your Next Test
Systemic infections can be caused by bacteria, viruses, fungi, or parasites.
Common symptoms include fever, chills, fatigue, and signs specific to affected organs.
Sepsis is a severe form of systemic infection that can lead to organ failure and death.
Diagnosis often involves blood cultures and imaging studies to identify the pathogen and extent of spread.
Treatment typically includes broad-spectrum antibiotics or antivirals followed by targeted therapy based on culture results.