Oxamniquine
from class: Microbiology Definition Oxamniquine is an antiparasitic medication used to treat schistosomiasis, a disease caused by parasitic worms. It acts by inducing paralysis and death in the parasites.
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Predict what's on your test 5 Must Know Facts For Your Next Test Oxamniquine is primarily effective against Schistosoma mansoni species. It functions by causing spastic paralysis of the schistosomes, leading to their detachment from blood vessels. Oxamniquine is administered orally and undergoes extensive first-pass metabolism in the liver. The drug can cause side effects such as dizziness, drowsiness, and gastrointestinal disturbances. Resistance to oxamniquine has been reported but is relatively rare. Review Questions What type of infection is oxamniquine used to treat? Describe the mechanism of action for oxamniquine. What are common side effects associated with oxamniquine?
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