Ergosterols

Definition

Ergosterols are a group of sterol compounds that form an essential component of fungal cell membranes, similar to cholesterol in animal cells. They play a crucial role in maintaining cell membrane integrity and fluidity.

5 Must Know Facts For Your Next Test

1. Ergosterols are unique to fungi and some protists, making them a target for antifungal drugs.
2. They serve as precursors for the synthesis of vitamin D2 when exposed to UV light.
3. Azole antifungal medications work by inhibiting ergosterol biosynthesis, disrupting the fungal cell membrane.
4. The presence of ergosterol is often used as a biomarker for fungal contamination in various environments.
5. Mutations affecting ergosterol synthesis can lead to resistance against certain antifungal treatments.

Review Questions

Related terms

Chitin:

A long-chain polymer that serves as a structural component in fungal cell walls.

Azoles:

A class of antifungal drugs that inhibit the synthesis of ergosterol.

Mycology:

The branch of biology concerned with the study of fungi.