🔬general biology i review

Telophase II

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Telophase II is the final stage of meiosis II, where the separated chromatids reach the opposite poles of the cell, and nuclear membranes re-form around each set of chromosomes. This stage signifies the conclusion of the meiotic division, resulting in four haploid cells from one original diploid cell. It’s essential for understanding how gametes are produced and how genetic diversity is achieved through meiosis.

5 Must Know Facts For Your Next Test

  1. During telophase II, chromosomes begin to decondense back into chromatin as the nuclear envelope reforms around them.
  2. This phase is followed by cytokinesis, which completes the process of cell division and results in four non-identical haploid cells.
  3. Telophase II occurs after anaphase II and is crucial for ensuring that each daughter cell receives a complete set of genetic material.
  4. In organisms that undergo sexual reproduction, telophase II is vital for generating gametes such as sperm and eggs, contributing to genetic variation.
  5. Errors during telophase II can lead to aneuploidy in gametes, which can result in conditions like Down syndrome if fertilization occurs with an abnormal gamete.

Review Questions

  • How does telophase II contribute to genetic diversity in gametes?
    • Telophase II is critical for genetic diversity because it ensures that each of the four resulting haploid cells has a unique combination of chromosomes. During meiosis, crossing over occurs in prophase I, and independent assortment happens during metaphase I, leading to variations. When telophase II occurs, the reformation of nuclear membranes around separated chromatids results in diverse genetic material being packaged into distinct gametes.
  • Compare telophase I and telophase II in terms of their roles within meiosis.
    • Telophase I and telophase II serve similar functions in that they both involve the reformation of nuclear envelopes around chromosome sets. However, telophase I concludes the first meiotic division, resulting in two haploid cells with duplicated chromosomes, while telophase II finalizes meiosis by producing four haploid cells from those two. The key difference lies in the chromosome state: telophase I involves homologous chromosomes, while telophase II deals with sister chromatids.
  • Evaluate the consequences of improper separation during telophase II and its impact on genetic outcomes.
    • Improper separation during telophase II can lead to aneuploidy, which is when cells have an abnormal number of chromosomes. This occurs if sister chromatids fail to separate correctly, resulting in gametes that may contain either too many or too few chromosomes. When these abnormal gametes participate in fertilization, it can lead to various genetic disorders or developmental issues, such as Down syndrome caused by an extra chromosome 21. Understanding these consequences highlights the importance of precise chromosomal movements during this crucial stage of meiosis.

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