🔬general biology i review

Phosphoanhydride bonds

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Phosphoanhydride bonds are high-energy bonds found between the phosphate groups in ATP molecules. Their hydrolysis releases significant energy, which is used to drive various cellular processes.

5 Must Know Facts For Your Next Test

  1. Phosphoanhydride bonds are located between the phosphate groups in ATP and ADP.
  2. The hydrolysis of these bonds releases approximately 30.5 kJ/mol of energy under standard conditions.
  3. Breaking a phosphoanhydride bond in ATP results in the formation of ADP and an inorganic phosphate (Pi).
  4. These bonds are less stable due to electrostatic repulsion between negatively charged phosphate groups.
  5. Enzymes such as ATPases catalyze the hydrolysis of phosphoanhydride bonds during cellular activities.

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