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Antagonist

Definition

In psychology, an antagonist is a substance that blocks or inhibits the function of a neurotransmitter in the brain.

Analogy

Think of an antagonist as a bouncer at a club. The neurotransmitters are party-goers trying to get inside (the receptor sites). The antagonist (bouncer) prevents certain party-goers (neurotransmitters) from entering, thus controlling who gets to influence the mood of the club (brain).

Related terms

Agonist: A substance that initiates a physiological response when combined with a receptor.

Neurotransmitter: Chemicals that transmit signals across a synapse from one neuron to another 'target' neuron.

Receptor Site: A part of a nerve cell where specific neurotransmitters can fit like keys into locks.

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AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.