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Major Depressive Disorder

Written by the Fiveable Content Team โ€ข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโ€ขWritten by the Fiveable Content Team โ€ข Last updated September 2025

Definition

Major Depressive Disorder is a mood disorder characterized by persistent feelings of sadness, hopelessness, loss of interest or pleasure in activities, changes in appetite or sleep patterns, difficulty concentrating, and thoughts of suicide. These symptoms must persist for at least two weeks and significantly impair daily functioning.

"Major Depressive Disorder" also found in: