💀anatomy and physiology i review

Granzyme

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Granzymes are serine proteases released by cytotoxic T cells and natural killer (NK) cells that induce apoptosis in target cells infected by viruses or transformed by cancer. They penetrate the target cell's membrane and trigger a cascade of reactions leading to cell death.

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