Lean manufacturing focuses on maximizing customer value while minimizing waste. It aims to create more value with fewer resources by identifying and eliminating non-value-adding activities in design, production, supply chain management, and customer service. Key principles include defining value, mapping the value stream, creating flow, establishing pull, and seeking perfection. Lean manufacturing tools like 5S, Just-in-Time production, and Kanban help organizations implement these principles and continuously improve their processes.