Microsatellite polymorphisms

Definition

Microsatellite polymorphisms are variations in the number of tandem repeat units at specific loci in DNA. These variations, often used as genetic markers, are highly mutable and can be used for genome mapping and studying genetic diversity.

5 Must Know Facts For Your Next Test

1. Microsatellites consist of short, repetitive DNA sequences typically 1-6 base pairs long.
2. They are also known as Short Tandem Repeats (STRs).
3. Microsatellite polymorphisms are highly variable among individuals, making them useful for genetic linkage analysis.
4. They are commonly used in forensic analysis, paternity testing, and population genetics studies.
5. PCR (Polymerase Chain Reaction) is often used to amplify microsatellite regions for analysis.

Related terms

Genetic Marker: A gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species.

PCR (Polymerase Chain Reaction): A laboratory technique used to make multiple copies of a segment of DNA.

Genetic Linkage Analysis: A method used to locate genes associated with diseases by studying the recombination frequency between different loci.