Heavy chain

Definition

A heavy chain is one of the two types of polypeptide chains found in an antibody molecule, characterized by its larger molecular weight compared to the light chain. It plays a crucial role in determining the class and function of an antibody within the adaptive immune response.

Related terms

Antibody: A protein produced by B-lymphocytes that binds to specific antigens, marking them for destruction by the immune system.

Light Chain: The smaller polypeptide chain component of an antibody that pairs with a heavy chain to form a functional antigen-binding site.

B: lymphocytes - A type of white blood cell that matures in bone marrow and produces antibodies in response to antigens, playing a key role in the adaptive immune system