🥼organic chemistry review

Oximes

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Oximes are organic compounds that result from the reaction of hydroxylamine (NH2OH) with an aldehyde or ketone, where a carbon-nitrogen double bond (C=N) is formed, replacing the carbon-oxygen double bond (C=O) of the aldehyde or ketone. This process is a specific example of nucleophilic addition involving the attack of an amine on a carbonyl group, leading to imine derivatives where the imine nitrogen bears a hydroxyl (OH) group.

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