FADH2

Definition

FADH2 is a reduced form of flavin adenine dinucleotide, a coenzyme involved in various metabolic processes. It plays a crucial role in the electron transport chain and cellular respiration.

5 Must Know Facts For Your Next Test

1. FADH2 is produced during the Krebs cycle when succinate is converted to fumarate.
2. Each FADH2 molecule can generate approximately 1.5 ATP molecules through oxidative phosphorylation.
3. FADH2 donates electrons to Complex II (succinate dehydrogenase) in the electron transport chain.
4. It differs from NADH in that it contributes fewer ATP molecules per molecule during cellular respiration.
5. The oxidation of FADH2 involves the transfer of electrons and protons to ubiquinone (coenzyme Q).

Review Questions

Related terms

NADH:

A coenzyme that carries electrons from glycolysis and the Krebs cycle to the electron transport chain.

Krebs Cycle:

A series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate.

Oxidative Phosphorylation:

The metabolic pathway where cells use enzymes to oxidize nutrients, thereby releasing energy used to produce ATP.