Primary effusion lymphoma is a type of cancer that arises from B cells and is associated with infections caused by the Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8). This lymphoma typically presents as pleural or peritoneal effusions, meaning it often manifests in the form of excess fluid in body cavities rather than a mass or tumor. It is predominantly seen in immunocompromised individuals, particularly those with HIV/AIDS, linking it closely to herpesvirus pathogenesis and the immune response.
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