Yeast two-hybrid is a molecular biology technique used to identify and study protein-protein interactions in living cells. This method leverages the yeast Saccharomyces cerevisiae, utilizing transcriptional activation to detect when two proteins interact, leading to the expression of a reporter gene. It has become a powerful tool in proteomics, enabling researchers to map out complex interaction networks within cells.
congrats on reading the definition of yeast two-hybrid. now let's actually learn it.